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Vortrag von Lena Pernas

Vortragstitel: "Remodeling of mitochondria during microbial infection"
Anlass: SFB Seminar
Host: Katia Cosentino
Beginn: 15.06.2023 - 16:15 Uhr
Ort: CellNanOs, 38/201

Über die Vortragende: Lena Pernas forscht zum Thema Stoffwechsel von Infektionen im Max Planck Institut für Biologie des Alterns in Köln.

Inhalt des Vortrags: The rewiring of mitochondrial metabolism serves as an innate immune-type defense mechanism that restricts the growth of the human parasite Toxoplasma gondii. We recently reporteda previously undescribed structure we term SPOT (structure positive for outer mitochondrial membrane (OMM) that emerges from the OMM during infection. We propose that Toxoplasma hijacks the formation of SPOTs, a cellular response to OMM stress, to promote its growth. Here, I discuss the fate and function of these peculiar structures.